Quality standards for Bhunimbadi Kvatha Curna
Introduction: Bhūnimbādi Kvātha cūrṇa (BKC) is a polyherbal formulation, compounded from parts of Swertia chirata Buch.Ham, Aconitum heterophyllum Wall. ex. Royle, Symplocos racemosa Roxb., Cyperus rotundus Linn., Holarrhena antidysenterica Wall., Coleus vettiveroides K. C. Jacob, Coriandrum sativum Linn., and Aegle marmelos Corr. as per formula composition in Ayurvedic Formulary of India. It is used in the treatment of asthma, cough, fever due to pitta dosa, bleeding disorder and fever. It is a popular medicine for cure of digestive impairments in fevers of different types, and many other clinical conditions. Though herbal medicines are effective, becoming popular, but they lack standardization. Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of the drug. Methods: In the present study BKC was subjected to organoleptic, macro-microscopic, physicochemical, HPTLC and 1H NMR characterization employing standard methodology mentioned in API and specified protocols. Results: Organoleptic characters, macro – microscopy, physico-chemical studies viz. total ash, water soluble ash, acid insoluble ash, water, alcohol and hydro – alcohol soluble extractive, loss on drying at 105°C, pH successive extractive values by Soxhlet extraction method and HPTLC and 1H NMR were recorded. Conclusion: A monograph on quality standards for BKC is proposed from the data obtained. The results of the present investigation would serve as a document to control the quality of the multiherb formulation BKC.