Pharmaceutico-analytical Study of Amrutottara Arka

Introduction: Amrutottara Kwatha is a very common formulation used for Jwara (Fever). Its taste and shelf life are the drawback of the dosage form to implement this into prescriptions. If the same could be modified into a form which would render same results as that of the Kwatha (decoction) it would be a better dosage form. Another dosage form namely Arka (distillate) is also an important because the preparation is also water based, it has good patient compliance and long shelf life. Methods: In this study Amrutottara or Nagaradi Kwatha consisting of Nagara (Zingiber officinale) Amruta (Tinospora cordifolia), Haritaki (Terminalia chebula) in 2:6:4 ratio) was converted into Arka. Amrutottara Arka (AA) was prepared in two strengths 1:16 and 1:2. 1:16 that is maximum ratio of Kwatha mentioned in Sharangadhara samhita and 1:2 that is one of ratio of Arka mentioned in Arka prakasha. The Pharmaceutical data were observed and recorded. Results: Analysis of both prepared medicines was carried out as per the protocols laid down by Ministry of AYUSH, Govt of India for Arka. Pharmaceutically 1:16 is better than 1: 2 ratio as easy in extraction of Arka 1:16 ratio and 1:2 ratio is having more shelf life compared to 1:16 ratio as it was not getting contaminated. Conclusion: The Analytical studies including HPTLC have helped to generate preliminary standards for both samples of Arka.