GCMS Study of Taila (medicated oil) and Kashaya (decoction) Kalpana of Nirgundi (Vitex negundo Linn.)

Introduction: Sesame oil is the base for preparation of most of the medicated oils used in Ayurvedic treatments. The oil is beneficial in the management of vata diseases. The leaf of Vitex negundo Linn. is indicated in pain dominant vata diseases. The leaf processed with sesame oil and leaf in water media (as decoction) is used in different procedures to manage painful vata conditions. Methods:  Gas chromatography coupled with mass spectroscopy (GCMS) has been used for detection and identification of volatile components from the oil of Sesamum indicum DC of Pedaliaceae, medicated oil and decoction from the leaf of V. negundo of Verbenaceae. Results: 26 compounds were identified in Tilataila (Sesame oil), 22 compounds were identified in Nirgunditaila (medicated oil prepared from V. negundo) and 30 compounds were identified in Nirgundikashaya (decoction of V. negundo). Comparatively 9 compounds identified were common to both Tilataila and Nirgunditaila. Only one compound Hentriacontane was found to be common with Nirgunditaila and Nirgundikashaya. Conclusion: This study has revealed the chemical composition of sesame oil, medicated oil and kashaya (decoction) of V. negundo and can serve as standard reference for identification and initial step for further studies like absorption study and so on.